Short Communication
Volume 1 Issue 6 - 2018
Title Mindset Kinetics –Under Toxicological Aspect
Luisetto Mauro1*, Behzad Nili-Ahmadabadi2 and Ghulam Rasool Mashori3
1Luisetto M Applied pharmacologist 29121 independent researcher, Italy
2Pharm D/PhD innovative Pharmaceutical product development specialist, USA
3Ghulam Rasool Mashori, Department of Medical & Health Sciences for Woman, Peoples University of Medical and Health Sciences for Women, Pakistan
*Corresponding Author: Luisetto M, Applied pharmacologist 29121 independent researcher, Italy.
Received: January 05, 2018; Published: January 10, 2018
Introduction
We can see that the AMOUNT of stressant stimulus and related KINETICS are relevant factors involved in some human conditions. Not only the single stress but the global amount in a limited time are involved in this situation and a chronic condition make more severe this situation. The same not all individuals react the same level and not all have resilience ability as needed.
But the single resilience ability depend only from psycologic status? Or other factors are involved?
Can we compare the mindset kinetics to other methabolic kinetics? Are really so different this aspects?
Can we think to a sort of saturate condition in some situation?
Can we think to a maximal velocity in management of simultaneous or high stressant stimulus?
Why some individuals react in very different way? Can we apply E. Goldratt TOC Theory of constraints in this kind of situations to explain some? Psychological pathways? Brain and mind follow the same principle? (limitanting factors?)
“We start our paper observing that in past centuries physicians in some cardiologic disease were used to prescribe to the patient to take a long rest in order to recuperate their health status. In past centuries it wasn’t available high efficient drugs strategies and so to take a long rest without physical and psychological stress contributes to this process.
Also in oriental medicine we can see body balances strategies, and also in some psycoaanalitc techniques we can see that time is relevant to re-equilibrate some conditions (in example acute stress). We can think that the main factors involved are TIME and LONG REST in order to balance the physiologic functions. In some case it was observed complete resolve in some situations. In example we can think that a metabolic unbalances can create this situation and the time make possible to restore.” [1]
“As observed in other scientific or medical discipline controlling some non-physiological cellular activity results in reducing of abnormal organ activation.
The same way we can think that some neuronal transmission pathway can be better pharmacologically modulate in order to have an example relevant reduction in amygdala disfuntions.” [2]
“Emotional processing and learning, and several social and affective decision making Functions are impaired in psychopathy, which correlates with specific changes in neural functions” [3]
“About 70% of works ability and success depends on emotional intelligence versus 30% technical abilities (Remember Pareto paradigm 20/80 similar). The emotional intelligence theory shows that the emotional brain can be more rapid in responding to some stress stimulus then the rational thinking. For example studies showed that Amygdala physio-pathology is involved in E. I. management and can give in this situation rapid response without waiting for the cortical brain control. (Neo-cortex/reptilian brain) [1]. When in the same time many strong emotions stimulation arrives too fast to amygdala the neo cortex is not involved [1]. An easy reactive amygdala can results in working difficulties in relationship in equip.
Low level of social intelligence gives isolation and depression and low working performances. Conflict are natural in all context and so in working setting. The self-motivation is strongly involved in professional development.
Successful status is related with high emotional, social and political attitudes. But even if the technical competences are subjects of usual educational and university policy we see a real gap for the emotional social and relational development in student curriculum. So in this work, we try to give some elements for improving behavior skills to be active and efficient part of a professional team or to prevent and resolve conflict.
In our opinion some theory are to be post under right light: and for example: De Bono Seven hats and Lateral thinking (problem solving approach), E. Goldratt TOC Theory of constraints, about psychological limits (a management theory), translational analysis, emotional and social intelligence, Pareto paradigm, GANTT diagram, Eisenhower matrix, Deming cycle (total quality management), MASLOV hierarchy of need, but they only the first of many other.”[5]
Discussion and Conclusion
Under the light of the citated literature and other biomedical article available we can observe that in order to evaluate stressing situation are fundamental:
  • kind of stress (in example HIGH or not)
  • Amount of global stressing condition, simultaneous
  • Duration of stimulus (cronic conditions?)
  • Individual status (resilience? stress management ability, depression ET other) psycologic but also genetic
  • Kinetics
We have seen that in order to improve resilience abilities are use full many techniques (5) in order to balance the mindset activity.
If unbalanced results in an inadeguate kinetics with an inappropriate global response.
We think that also this condition must be evaluated under a kinetic- toxicological aspect to clear the basic Phisio-patogenetic movens. A deep knowledge in some process can be usefull also in pharmacological new startegies finding today not travelled as request.
References
  1. Luisetto M. “Intra- Local Toxicology Aspect Time Related in Some Pathologic Conditions”. Open Access Journal of Toxicology 2.3 (2017).
  2. Luisetto M. “Brain and Transmission Signal Modulation”. Theranostics of Brain Disorders 1.1 (2017).
  3. Del casale et al. “Functional Neuroimaging in Psychopathy”. Neuro psychobiology 72.2 (2015): 97–117.
  4. Mauro L., et al. “Amygdala pharmacology and crime behavior, dysfunctions to be considered as a disease?” IABCR International Archives of Biomedical and Clinical Research 2.2 (2016).
  5. Mauro L. “Attitudes and Skills in Business Working Settings: A HR Management Tool”. Business and Economics Journal 8 (2017): 291.
Citation: Luisetto M., et al. “Title Mindset Kinetics –Under Toxicological Aspect”. Chronicles of Pharmaceutical Science 1.6 (2018): 369-371.
Copyright: © 2018 Luisetto M., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.